WebDec 26, 2024 · The Apoptosis-Inducing Factor (AIF) is a moonlighting flavoenzyme involved in the assembly of mitochondrial respiratory complexes in healthy cells, but also able to trigger DNA cleavage and parthanatos. Upon apoptotic-stimuli, AIF redistributes from the mitochondria to the nucleus, where upon associ … WebFeb 17, 2024 · In vitro studies revealed that maltol protected SH‑SY5Y cells against OGD‑induced chromatinolysis by inhibiting two reactive oxygen species (ROS)‑regulated pathways. One was DNA double‑strand breaks and the other was nuclear translocation of apoptosis inducing factor. Mechanistically, maltol not only inhibited OGD‑induced …
Chromatinolysis definition of chromatinolysis by
WebDefine chromatinolysis. chromatinolysis synonyms, chromatinolysis pronunciation, chromatinolysis translation, English dictionary definition of chromatinolysis. n. The dissolution or disintegration of chromophil material, such as chromatin, within a cell. chro·mat′o·lyt′ic adj. American Heritage® Dictionary of the... WebIn cellular neuroscience, chromatolysis is the dissolution of the Nissl bodies in the cell body of a neuron. It is an induced response of the cell usually triggered by axotomy, ischemia, … magic shops in myrtle beach
Necroptosis and tumor progression - ScienceDirect
WebDec 26, 2024 · However, the depletion of these nucleases resulted in lower levels of chromatinolysis and cell death induced by MNNG, while the depletion of AIF was an … WebJun 23, 2013 · The apoptosis-inducing factor (AIF) is a mitochondrial-flavoprotein that, after cell death induction, is distributed to the nucleus to mediate chromatinolysis. In mitochondria, AIF is present in a monomer-dimer equilibrium that after reduction by NADH gets displaced toward the dimer. The crystal structure of the human AIF (hAIF):NAD (H) … WebAug 29, 2024 · Chromatinolysis is considered as one of the key events leading to cell death during necroptosis. It is usually accompanied with nuclear translocation of AIF … magic shops denmark