WebOverexpression of FOXM1 has been reported in more than 20 types of human cancer. In recent years, FOXM1 has been implicated in diverse cellular processes and also a … WebNov 14, 2012 · FoxM1 is a key protein controlling the G 1 to S and G 2 to M checkpoints; thus, it will be interesting to determine the role of miRNA in the regulation of FoxM1 during the maturation of cancer stem cells. Furthermore, it will be interesting to determine whether the same miRNAs modulate the function of FoxM1 and Wnt/β-catenin signaling, hence ...
Effective combination treatments for breast cancer inhibition by FOXM1 …
WebJun 8, 2011 · Consistent with this notion, FOXM1 has been found to be frequently upregulated in a host of human cancers, including colorectal ( 23 ), lung ( 24 ), prostate ( 25 ), liver ( 26 ), stomach ( 38 ), breast ( 27 ), and basal cell carcinomas ( 39) as well as glioblastoma ( 40 ). WebJan 31, 2024 · Objective . The aim of the present study was to investigate the effect of forkhead box M1 (FOXM1) to paclitaxel resistance in cervical cancer cells, to determine the underlying mechanism, and to identify novel targets for the treatment of paclitaxel-resistant cervical cancer. Methods . Paclitaxel-resistant Caski cells (Caski/Taxol cells) were … reflection\u0027s yx
FOXM1 Inhibition Enhances the Therapeutic Outcome of Lung Cancer I…
WebMay 1, 2024 · FOXM1 promoted the tumorigenesis of CRC in vitro To explore the effects of FOXM1 on CRC progression in vitro, we obtained FOXM1 upregulating and downregulating cells for our subsequent experiments in vitro. WebOct 25, 2024 · In esophageal cancer, FOXM1 has been related to cell growth, proliferation, and metastasis [49,61,62] and plays a key role in both PTX resistance in breast cancer and ovarian cancer . Wang et al. reported that UA inhibits the proliferation of breast cancer cells by suppressing the expression of FOXM1 . Therefore, it can be hypothesized that UA ... WebMar 7, 2014 · FOXM1 is a transcription factor that transactivates AURKA and other G2/M genes like PLK1, CDK1, and CCNB1 (16) (17) (18). High FOXM1 expression was reported in many cancers including oral... reflection\u0027s yo